Like any self respecting firearm enthusiast I always have some number of projects going on concurrently. One of them is a fast twist 22-250 bolt gun.
Every once in a while Tikka makes a run of 22-250 T3x rifles with 1-8” twist barrel and I happen to have one. That dramatically changes the varminty character of the 22-250. With a modern 80gr bullet, it is a nicely viable hunting rifle for small and medium game (just about perfect for pronghorn). It is also a very capable long range number. At the altitude where I live, it does not go subsonic until you get to about 1400 yards.
1-8” twist will not stabilize the heaviest available 22 bullets, but works well enough for anything up to about 80grains, depending on the bullet construction.